Arava Lawyer

Arava Lawyer

Facts on Arava
More than 2 million Americans suffer from rheumatoid arthritis, which is an autoimmune disease where the patient's own immune system attacks the joint cartilage, the cushiony material that keeps the joints moving slowly.
Rheumatoid arthritis afflicts children and adults, with three times as many women as men suffering from the disease. Two Arava deaths have been people in their 20s.
Aventis Pharmaceuticals have reported $225 million in sales for Arava in 2001.
The FDA has six times more reports of liver damage among Arava users than methotrexate users, despite methotrexate being prescribed 5.5 times more than Arava.
Former FDA scientific adviser and Director of Arizona Arthritis Center, David Yocum pointed out that most health plans require doctors to prescribe Arava before resorting to two new rheumatoid arthritis drugs because they are far more expensive.
The FDA has six times more reports of liver damage among Arava users than competitor methotrexate users, despite methotrexate being prescribed 5.5 times more than Arava.
Public Citizen filed a petition to the FDA urging the immediate ban of Arava from the market, finding Arava's risks outweigh its benefits, which are no better than those offered by an older, commonly used treatment.

ADVERSTISEMENT
arava drug recall

Arava Lawyer

If you suffer from Arava side effects, contact an Arava lawyer!

"With a variety of better drug treatments available, there is no reason to subject patients to an accumulating list of added risks. (Arava) should be promptly removed from the market."
-from the Public Citizen petition to the FDA requesting Arava be immediately banned
Arava Patient Death Rate Climbing
More than two hundred thousand patients have used rheumatoid arthritis drug Arava (leflunomide) since its FDA approval in September 1998. When approved, the FDA said Arava was no better than competitor methotrexate but felt rheumatoid patients needed options. The option appears to have been a dangerous one to Arava patients because of the death rate being 33 times higher than methotrexate patients.

Arava Banned?
On March 28th, the consumer advocacy group Public Citizen filed a petition to the FDA urging an immediate ban on the sales of Arava due to the 12 liver failure deaths associated to the drug. This petition was not the first indicator that serious and deadly Arava side effects can occur.

Serious Arava Side Effects
  • Liver Damage, Liver Failure (Hepatoxicity)
  • Lymphoma
  • Drug Induced Hypertension
  • Stevens-Johnson Syndrome
Arava Warning Letter
In February 2001, the European Agency for the Evaluation of Medical Products issued a warning to doctors and patients citing nine liver failure deaths in Arava patients. Aventis Pharmaceuticals, Arava's manufacturer, issued a warning letter to physicians two months later. The American College of Rheumatology published a warning to doctors and patients in August to warn of the serious potential Arava side effects by urging monthly blood tests in a patient's first six months on the drug with follow up tests every two to three months after.

The FDA is currently considering Public Citizen's petition. Arava is also dangerous because it remains in the body tissues for an extended amount of time. Patients who have discontinued their use of Arava due to adverse effects can continue to experience the symptoms because of this.

If you would like more information on your rights regarding Arava side effects contact us to speak directly with an expert Arava attorney.

March 29, 2002, MSNBC
Rheumatoid arthritis drug Arava (leflunomide) is linked to at least 12 liver failure deaths.
Public Citizen filed a petition to the FDA urging them to review the unexpected deaths and serious illnesses that have been attributed to the use of Arava (leflunomide). Former FDA scientific adviser Dr. David Yocum supports Public Citizen's petition because "here we have 12 deaths, and these patients died very quickly. All I can say is, this needs to be reviewed."

click here to speak to an arave lawyer todayPublic Citizen's petition followed the February 2001 European Agency for the Evaluation of Medical Products warning issued to doctors and patients citing nine liver failure deaths in Arava patients. Two months following, Arava manufacturer Aventis Pharmaceuticals issued a warning letter to physicians. Last August, the American College of Rheumatology then published a warning to doctors and patients urging a monthly blood test be performed in an Arava patient's first six months with follow up tests every two to three months after. Yocum said he has never supported taking a drug off the market, "but it's kind of scary, what we see." (MSNBC, 3-29-02) >read more news on Arava!

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Arava Side Effects
Director of Arizona Arthritis Center and former scientific adviser to the FDA, Dr. David Yocum, says it is impossible to predict which patients will be at risk, making Arava use dangerous due to the serious and fatal complications associated to the rheumatoid arthritis drug. Yocum feels, "I do not believe that the general rheumatologist understands or has any knowledge about these serious and potentially life-threatening complications." (Yahoo, 3-28-02) >read more about Arava side effects!

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About Rheumatoid Arthritis (RA)
Rheumatoid arthritis (RA) is the inflammation of the lining of the joints and/or other internal organs, typically affecting many different joints. Rheumatoid arthritis can be a chronic condition that affects the entire body. >read more about RA!

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Rheumatoid Arthritis Treatment Options
There is no cure for rheumatoid arthritis (RA) at this time, but treatment options, like leflunomide (Arava) have been created to manage the pain and swelling that occurs in the joints. There are currently no real effective treatment options due to the serious adverse effects that are associated to rheumatoid arthritis prescription drugs, such as leflunomide (Arava). >read more about treatment options!

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Reporting Arava Adverse Effects to the FDA
MedWatch is the FDA's program that allows consumer to report serious reactions and problems with medical products. So far, there have been at least 130 cases of severe liver problems (hepatoxicity) and 22 deaths since Arava's arrival to the market in 1998. It is estimated that there is a 10-100 fold of underreporting that occurs with a drug's adverse effects. >read more on reporting adverse effects!

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Rheumatoid arthritis (RA) involves inflammation in the lining of the joints and other internal organs. Unlike other types of arthritis that normally affects the elderly, rheumatoid arthritis' onset is between ages 25 and 50.

Common symptoms of rheumatoid arthritis includes:

  • Loss of appetite
  • Fever
  • Loss of energy
  • Anemia
  • Sometimes rheumatoid nodules (lumps of tissue under the skin)
  • Can affect other parts of the body