Arava Side Effects

Arava side effects have been the link to at least 130 cases of severe liver problems (hepatoxicity) and 22 deaths since its arrival to the market in 1998. The rheumatoid arthritis drug has also been linked to lymphoma, high blood pressure, and Stevens-Johnson syndrome.

Liver failure: Arava side effects include Liver failure

Stevens-Johnson syndrome: Stevens-Johnson syndrome is an immune complex mediated hypersensitivity complex that is a severe expression of erythema multiforme.

In the Arava prescribing information, the following adverse reactions have been reported in the controlled studies performed on the rheumatoid arthritis drug, regardless of causality.

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Arava Side Effects:

Body as a whole: allergic reaction, asthenia, flu syndrome, infection, injury accident, pain, abdominal pain, back pain, abscess, cyst, fever, hernia, malaise, pain, neck pain, pelvic pain

Cardiovascular: hypertension, chest pain, angina pectoris, migraine, palpitation, tachycardia, varicose vein, vasculitis, vasodilatation

Gastrointestinal: anorexia, diarrhea, dyspepsia, gastroenteritis, abnormal liver enzymes, nausea, GI/abdominal pain, mouth ulcer, vomiting, cholelithiasis, colitis, constipation, esophagitis, flatulence, gastritis, gingivitis, melena, oral moniliasis, pharyngitis, salivary gland enlarged, stomatitis, tooth disorder

Endocrine: diabetes mellitus, hyperthyroidism

Hemic and lympathic system: anemia, ecchymosis

Metabolic and nutritional: hypokalemia, weight loss, creatine phosphokinase increased, hyperglycemia, hyperlipidemia, peripheral edema

Musculo-skeletal system: arthralgia, leg cramps, joint disorder, synovitis, tenosynovitis, arthrosis, bone necrosis, bone pain, bursitis, muscle cramps, myalgia, tendon rupture

Nervous system: dizziness, headache, paresthesia, anxiety, depression, dry mouth, insomnia, neuralgia, neuritis, sleep disorder, sweating increased, vertigo

Respiratory system: bronchitis, increased cough, respiratory infection, pharyngitis, pneumonia, rhinitis, sinusitis, asthma, dyspnea, epistaxis, lung disorder

Skin and appendages: alopecia, eczema, pruritus, rash, dry skin, acne, contact dermatitis, fungal dermatitis, hair discoloration, hematoma, herpes simplex, herpes zoster, maculopapular rash, nail disorder, skin discoloration, skin disorder, skin nodule, subcutaneous nodule, ulcer skin

Special senses: blurred vision, cataract, conjunctivitis, eye disorder, taste perversion

Urogenital system: urinary tract infection, albuminuria, cystitis, dysuria, hematuria, menstrual disorder, prostate disorder, urinary frequency, vaginal moniliasis

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